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Federal Forecasted GRANTS-GOV-363680

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2

National Institutes of Health (NIH) · Competitive grant · Science & Technology

At a glance

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 is a federal competitive grant from National Institutes of Health for the science & technology sector. Funding is up to $1M. Eligible applicants: Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Special district governments; Native Ame. Applications are accepted on a rolling basis. Apply via the official listing at www.grants.gov.

Amount
Up to $1M
Deadline
Rolling
Type
Competitive
Status
Forecasted

About this program

NIDA seeks to further advance its mission in the area of single cell biology. Since 2020, the NIDA-funded Single Cell Opioid Responses in the Context of HIV (SCORCH) consortium has generated single-nucleus datasets from human and animal postmortem brain tissue under conditions of HIV infection, antiretroviral therapy (ART), and/or substance exposure (e.g. opioids, cocaine, methamphetamine, and cannabinoids). Building on this Phase 1 foundation, NIDA will encourage research addressing critical questions on Substance Use Disorder (SUD) and interactions with HIV disease progression at the subcellular, cellular, or circuit levels in the Central Nervous System (CNS). Many new cutting-edge single cell approaches (e.g. interrogation of RNA splicing, non-coding RNAs, epigenomic or proteomic features, subcellular or synaptic localization and function, spatial interactions, cell-cell communication, or cellular connectivity) now enable novel hypothesis-generating studies. Along with data mining studies to identify candidate mechanisms or targets contributing to HIV/SUD interactions and hypothesis-driven studies to assess functional significance, we expect SCORCH Phase 2 to significantly advance our mechanistic understanding of SUDs and HIV in the CNS and identify targets for novel therapies. Grant authorities that allow NIDA to forecast this opportunity are 42 U.S.C. §§ 241 and 284

Who can apply

Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Special district governments; Native American tribal governments (Federally recognized); Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Small businesses; For profit organizations other than small businesses; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification). Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

How to apply

Apply through Grants.gov using funding opportunity number RFA-DA-28-001. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.

Apply at official source