At a glance
Mechanistic Evaluation of Therapeutic Targets derived from Treatable Traits to Improve CNS Outcomes in People with HIV (R21/R33 Clinical Trial Not Allowed) is a federal competitive grant from National Institutes of Health for the science & technology sector. Eligible applicants: For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education. The application deadline is October 28, 2027. Apply via the official listing at www.grants.gov.
- Amount
- See listing
- Deadline
- Oct 28, 2027
- Type
- Competitive
- Status
- Open
About this program
The purpose of this notice of funding opportunity (NOFO) is to identify modifiable mechanisms and therapeutic targets to address central nervous system (CNS) complications associated with human immunodeficiency virus (HIV). The initiative supports a phased research approach beginning with the identification of patient phenotypes characterized by convergent pathophysiological features, followed by the discovery and experimental validation of molecular mechanisms using innovative in-vitro and in-vivo models. The goal of this NOFO is to advance therapeutic target, and intervention discovery to address the multifactorial and heterogeneous nature of HIV-associated CNS dysfunction.
Who can apply
For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; County governments; Private institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); City or township governments; Special district governments; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification). Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
How to apply
Apply through Grants.gov using funding opportunity number RFA-MH-27-125. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
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