At a glance
Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required) is a federal competitive grant from National Institutes of Health for the science & technology sector. Eligible applicants: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status wi. The application deadline is October 15, 2027. Apply via the official listing at www.grants.gov.
- Amount
- See listing
- Deadline
- Oct 15, 2027
- Type
- Competitive
- Status
- Open
About this program
This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure development (R61) followed by well-powered clinical trials (R33) to test the effectiveness of system interventions and strategies for improving the organization, delivery, coordination, and clinical and functional outcomes of mental health services. System interventions - which may span, for example, structural, policy, organizational, and interpersonal domains - attend to issues about the access, equity, engagement/utilization, value (cost/financing), management, or quality and safety of mental health services, with the goal of improved care processes and clinical and functional outcomes. Accordingly, the focus of system interventions may include a variety of care settings, such as health systems and organizations, mental health and community clinics, schools, and child welfare or juvenile justice systems
Who can apply
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Small businesses; Special district governments; Private institutions of higher education; State governments; Independent school districts; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); City or township governments. Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
How to apply
Apply through Grants.gov using funding opportunity number PAR-25-285. Register your organization (SAM.gov + Grants.gov) before the deadline, then submit the application package listed in the official notice.
Apply at official sourceRelated grants
- F26AS00030 Cooperative Endangered Species Conservation Fund: Recovery Land Acquisition Grant Program DOI · $10K–$14.2M · Nov 20, 2026 Open
- NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) NIH · See listing · Sep 7, 2027 Open
- Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required) NIH · See listing · Jan 6, 2028 Open
- Cannabis Research and Innovation Funding Opportunity (RIFO) Department of Fish and Wildlife · Dependant on number of submissions received, application process, etc. · Rolling Open